In this session, you can perform one or all three of the following exercises
Exercise: Measuring modification levels in our yeast dataset
In this exercise, we will measure modification levels at initiation sites and termination sites in our yeast dataset and compare them.
Exercise: Exploring yet another unknown BAM file
In this exercise, we will explore another BAM file and discover what is in it. Data is from Chen, HX., Liu, ZD., Bai, X. et al. Accurate cross-species 5mC detection for Oxford Nanopore sequencing in plants with DeepPlant. Nat Commun 16, 3227 (2025). The study is at this link.
Exercise: Exploring a fiberseq dataset
In this exercise, we will explore a chromatin stencilling method, Fiberseq, that allows experimentalists to imprint protein binding locations on single molecules of DNA. Data is from Mark Boltengagen, Daan Verhagen, Michael Roland Wolff, Elisa Oberbeckmann, Matthias Hanke, Ulrich Gerland, Philipp Korber, Felix Mueller-Planitz, A single fiber view of the nucleosome organization in eukaryotic chromatin, Nucleic Acids Research, Volume 52, Issue 1, 11 January 2024, Pages 166–185. The study is at this link.